Which of the following manifestations indicates worsening hypertensive disease during pregnancy?

Shortness of breath is a significant manifestation that can indicate worsening hypertensive disease during pregnancy, particularly conditions such as preeclampsia and gestational hypertension. This symptom may arise due to fluid accumulation in the lungs (pulmonary edema) or other cardiovascular complications that can occur as hypertension progresses. In pregnant individuals, such symptoms require prompt evaluation because they might indicate the need for more intensive monitoring or intervention to protect both maternal and fetal health.

In contrast, increased appetite, clearness of amniotic fluid, and regular daily physical activity are not typically associated with worsening hypertensive disease. These factors do not directly indicate a deterioration in the condition and may often reflect a stable or improving pregnancy state. Thus, recognizing and addressing shortness of breath as a potential warning sign is crucial for managing hypertensive disorders in pregnant individuals effectively.